Article
Beyond genome-wide association studies: the usefulness of mouse genetics in understanding the complex etiology of atherosclerosis.
Arteriosclerosis, thrombosis, and vascular biology - 1 Feb 2012
Welch Carrie L
Abstract excerpt
The development of population-based genome-wide association studies has led to the rapid identification of large numbers of genetic variants associated with coronary artery disease (CAD) and related traits. Together with large-scale gene-centric studies, at least 35 loci associated with CAD per se have been identified with replication. The majority of these associations are with common single-nucleotide...
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