Article
Laboratory mouse models for the human genome-wide associations.
PloS one - 1 Nov 2010
Kitsios Georgios D, Tangri Navdeep, Castaldi Peter J, Ioannidis John P A
Abstract excerpt
The agnostic screening performed by genome-wide association studies (GWAS) has uncovered associations for previously unsuspected genes. Knowledge about the functional role of these genes is crucial and laboratory mouse models can provide such information. Here, we describe a systematic juxtaposition of human GWAS-discovered loci versus mouse models in order to appreciate the availability of mouse models data, to...
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