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Article

Identifying novel genes for atherosclerosis through mouse-human comparative genetics.

American journal of human genetics - 1 Jul 2005

Wang Xiaosong, Ishimori Naoki, Korstanje Ron, Rollins Jarod, Paigen Beverly

Abstract excerpt

Susceptibility to atherosclerosis is determined by both environmental and genetic factors. Its genetic determinants have been studied by use of quantitative-trait-locus (QTL) analysis. So far, 21 atherosclerosis QTLs have been identified in the mouse: 7 in a high-fat-diet model only, 9 in a sensitized model (apolipoprotein E- or LDL [low-density lipoprotein] receptor-deficient mice) only, and 5 in both models,...

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Share to Arteriosclerosis
Share to Chromosome Mapping
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Lipoproteins, HDL

Share to Mice, Inbred Strains

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Share to Quantitative Trait Loci

Source

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Identifiers

PMID: 15931593
DOI: 10.1086/431656
PMCID: PMC1226181

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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