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Epithelial–mesenchymal plasticity and circulating tumor cells: Travel companions to metastases

13 Apr 2017

Abstract excerpt

Epithelial-mesenchymal transitions (EMTs) associated with metastatic progression may contribute to the generation of hybrid phenotypes capable of plasticity. This cellular plasticity would provide tumor cells with an increased potential to adapt to the different microenvironments encountered during metastatic spread. Understanding how EMT may functionally equip circulating tumor cells (CTCs) with an enhanced...

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PMID: 28407379
DOI: 10.1002/dvdy.24506

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