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Quantifying Cancer Epithelial-Mesenchymal Plasticity and Its Association with Stemness and Immune Response

2019-04-18

Abstract excerpt

Cancer cells can acquire a spectrum of stable hybrid epithelial/mesenchymal (E/M) states during epithelial-mesenchymal transition (EMT). Cells in these hybrid E/M phenotypes often combine epithelial and mesenchymal features and tend to migrate collectively commonly as small clusters. Such collectively migrating cancer cells play a pivotal role in seeding metastases and their presence in cancer patients indicates a...

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Literature Corpus work
3b7538f9-9914-5e46-a589-94db8d21186e
DOI
10.20944/preprints201904.0206.v1
Open publication

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Quantifying Cancer Epithelial-Mesenchymal Plasticity and Its Association with Stemness and Immune ResponseDOI 10.20944/preprints201904.0206.v1
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