Article

The Anti- <i>Burkholderia</i> Lasso Peptide Ubonodin Co-Opts the Siderophore Receptor PupB for Cellular Entry

2022-03-09

Abstract excerpt

<h4>ABSTRACT</h4> New antibiotics are needed as bacterial infections continue to be a leading cause of death. Notorious among antibiotic-resistant bacteria is the Burkholderia cepacia complex (Bcc), which infects cystic fibrosis patients, causing lung function decline. We recently discovered a novel ribosomally synthesized and post-translationally modified peptide (RiPP), ubonodin, with potent activity against s...

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Literature Corpus work: 350861c6-1151-5a65-94f8-2496ca046382
DOI: 10.1101/2022.03.09.483586

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