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Article

Structure and Function of the PiuA and PirA Siderophore-Drug Receptors from Pseudomonas aeruginosa and Acinetobacter baumannii.

Antimicrobial agents and chemotherapy - 1 Apr 2017

Moynié Lucile, Luscher Alexandre, Rolo Dora, Pletzer Daniel, Tortajada Antoni, Weingart Helge, Braun Yvonne, Page Malcolm G P, Naismith James H, Köhler Thilo

Abstract excerpt

The outer membrane of Gram-negative bacteria presents an efficient barrier to the permeation of antimicrobial molecules. One strategy pursued to circumvent this obstacle is to hijack transport systems for essential nutrients, such as iron. BAL30072 and MC-1 are two monobactams conjugated to a dihydroxypyridone siderophore that are active against Pseudomonas aeruginosa and Acinetobacter baumannii Here, we...

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Identifiers

PMID: 28137795
DOI: 10.1128/AAC.02531-16
PMCID: PMC5365723

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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