Article

Core variability in substitution rates and the basal sequence characteristics of the human genome

2015-08-10

Abstract excerpt

Accurate knowledge on the core components of substitution rates is of vital importance to understand genome evolution and dynamics. By performing a single-genome and direct analysis of 39894 retrotransposon remnants, we reveal germline sequence-dependent nucleotide substitution rates that can be assigned to each position in the human genome. Benefiting from the data made available in such detail, we show that a si...

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Literature Corpus work: 34f693c5-7511-5da2-bad4-43cb19829399
DOI: 10.1101/024257

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