Article

Genomic variants concurrently listed in a somatic and a germline mutation database have implications for disease-variant discovery and genomic privacy

2018-10-22

Abstract excerpt

<h4>Background</h4> Mutations arise in the human genome in two major settings: the germline and soma. These settings involve different inheritance patterns, chromatin structures, and environmental exposures, all of which might be predicted to differentially affect the distribution of substitutions found in these settings. Nonetheless, recent studies have found that somatic and germline mutation rates are similarl...

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Literature Corpus work: 61e7ee75-b8d4-5a79-9ce7-e8f711b00171
DOI: 10.1101/450239

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