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Article

DNA replication timing and selection shape the landscape of nucleotide variation in cancer genomes.

Nature communications - 1 Jan 2012

Woo Yong H, Li Wen-Hsiung

Abstract excerpt

Cancer cells evolve from normal cells by somatic mutations and natural selection. Comparing the evolution of cancer cells and that of organisms can elucidate the genetic basis of cancer. Here we analyse somatic mutations in >400 cancer genomes. We find that the frequency of somatic single-nucleot...

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PMID: 22893128
DOI: 10.1038/ncomms1982

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-22893128-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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