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Article

Single genome retrieval of context-dependent variability in mutation rates for human germline.

BMC genomics - 13 Jan 2017

Sahakyan Aleksandr B, Balasubramanian Shankar

Abstract excerpt

BACKGROUND: Accurate knowledge of the core components of substitution rates is of vital importance to understand genome evolution and dynamics. By performing a single-genome and direct analysis of 39,894 retrotransposon remnants, we reveal sequence context-dependent germline nucleotide substitution rates for the human genome. RESULTS: The rates are characterised through rate constants in a time-domain, and are...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 28086752
DOI: 10.1186/s12864-016-3440-5
PMCID: PMC5237266

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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