Article

Signatures of Mutational Processes in Human DNA Evolution

2021-01-09

Abstract excerpt

The human genome contains over 100 million SNPs, most of which are C/T (G/A) variations. The type and sequence context of these SNPs are not random, suggesting that they are caused by distinct mutational processes. Deciphering the mutational signatures is a crucial step to discovering the molecular processes responsible for DNA variations across human populations, and potentially for causing genetic diseases. Our...

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Literature Corpus work: 4a99f555-b727-538a-ad5e-f5b074bee237
DOI: 10.1101/2021.01.09.426041

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