Article

Machine learning sequence prioritization for cell type-specific enhancer design

2021-04-15

Abstract excerpt

Recent discoveries of extreme cellular diversity in the brain warrant rapid development of technologies to access specific cell populations, enabling characterization of their roles in behavior and in disease states. Available approaches for engineering targeted technologies for new neuron subtypes are low-yield, involving intensive transgenic strain or virus screening. Here, we introduce SNAIL (Specific Nuclear-A...

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Literature Corpus work: 34e80580-232c-5e5f-bc72-c03963b877f1
DOI: 10.1101/2021.04.15.439984

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