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Article

Genetic variation in cortico-amygdala serotonin function and risk for stress-related disease.

Neuroscience and biobehavioral reviews - 1 Sept 2008

Holmes Andrew

Abstract excerpt

The serotonin system is strongly implicated in the pathophysiology and therapeutic alleviation of stress-related disorders such as anxiety and depression. Serotonergic modulation of the acute response to stress and the adaptation to chronic stress is mediated by a myriad of molecules controlling serotonin neuron development (Pet-1), synthesis (tryptophan hydroxylase 1 and 2 isozymes), packaging (vesicular...

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Identifiers

PMID: 18439676
DOI: 10.1016/j.neubiorev.2008.03.006
PMCID: PMC2561331

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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