Article
Revealing the cerebral regions and networks mediating vulnerability to depression: oxidative metabolism mapping of rat brain.
Behavioural brain research - 1 Jul 2014
Harro Jaanus, Kanarik Margus, Kaart Tanel, Matrov Denis, Kõiv Kadri, Mällo Tanel, Del Río Joaquin, Tordera Rosa M, Ramirez Maria J
Abstract excerpt
The large variety of available animal models has revealed much on the neurobiology of depression, but each model appears as specific to a significant extent, and distinction between stress response, pathogenesis of depression and underlying vulnerability is difficult to make. Evidence from epidemiological studies suggests that depression occurs in biologically predisposed subjects under impact of adverse life...
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