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Article

Influence of sex and corticotropin-releasing factor pathways as determinants in serotonin sensitivity.

Endocrinology - 1 Aug 2009

McEuen Jonathan G, Semsar Katharine A, Lim Maria A, Bale Tracy L

Abstract excerpt

Stress sensitivity and sex are predictive factors in affective disorder susceptibility. Serotonin (5-HT) pathway recruitment by corticotropin-releasing factor (CRF) during stress is necessary in adaptive coping behaviors, but sex differences in such responses have not been investigated. Using selective 5-HT reuptake inhibitor (SSRI) administration to acutely elevate 5-HT in a genetic model of stress sensitivity,...

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Identifiers

PMID: 19342454
DOI: 10.1210/en.2008-1721
PMCID: PMC2717884

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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