Article

Hyperactivity of the Amygdala Mediates Depressive-Like Phenotypes and Decreased Serotonin Release

2025-08-27

Abstract excerpt

<title>Abstract</title> <p>Clinical and preclinical studies have consistently demonstrated a correlation between hyperactivity of the amygdala and the onset of depression. However, the underlying mechanisms influencing serotonin levels a critical neurotransmitter implicated in depression and a primary target for selective serotonin reuptake inhibitors (SSRIs) remain inadequately understood. In this study, we empl...

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Literature Corpus work: 05d243c2-f8b3-52f3-b688-8e80b91b1645
DOI: 10.21203/rs.3.rs-7251588/v1

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