Article

A BTB-Domain Transcription factor Recruits Chromatin Remodelers and a Histone Chaperone during the exit from Pluripotency

2020-12-06

Abstract excerpt

<h4>ABSTRACT</h4> Transcription factors (TFs) harboring a btb (Broad-Complex, Tramtrack and Bric a brac) domain play important roles in development and disease. They are thought to recruit transcriptional modulators to DNA through their btb domain. However, a systematic molecular understanding of this TF family is lacking. Here, we identify the zinc finger btb-TF Zbtb2 in a genetic screen for regulators of exit...

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Literature Corpus work: 3460f400-7425-5d41-9985-a8ed809bea7d
DOI: 10.1101/2020.12.03.409912

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