Article

Unveiling role of Sphingosine-1-phosphate receptor 2 as a brake of epithelial stem cell proliferation and a tumor suppressor in colorectal cancer

2020-10-13

Abstract excerpt

<h4>Background: </h4> Sphingosine-1-phosphate receptor 2 ( S1PR2 ) mediates pleiotropic functions encompassing cell proliferation, survival, and migration, which become collectively de-regulated in cancer. Information on whether S1PR2 participates in colorectal carcinogenesis/cancer is scanty, and we set out to fill the gap. <h4>Methods: </h4>. We screened expression changes of S1PR2 in human CRC and matched norma...

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Identifiers and source

Literature Corpus work: 343116f9-720f-5352-bdf5-15dc54b6d82c
DOI: 10.21203/rs.3.rs-56319/v2

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