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Article

Signaling pathways in intestinal homeostasis and colorectal cancer: KRAS at centre stage.

Cell communication and signaling : CCS - 10 Mar 2021

Ternet Camille, Kiel Christina

Abstract excerpt

The intestinal epithelium acts as a physical barrier that separates the intestinal microbiota from the host and is critical for preserving intestinal homeostasis. The barrier is formed by tightly linked intestinal epithelial cells (IECs) (i.e. enterocytes, goblet cells, neuroendocrine cells, tuft cells, Paneth cells, and M cells), which constantly self-renew and shed. IECs also communicate with microbiota,...

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Identifiers

PMID: 33691728
DOI: 10.1186/s12964-021-00712-3
PMCID: PMC7945333

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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