Article

Identification, Isolation, and Characterization of Human LGR5-positive Colon Adenoma Cells

2017-03-18

Abstract excerpt

<h4>ABSTRACT</h4> The intestine is maintained by stem cells located at the base of crypts and distinguished by the expression of LGR5. Genetically engineered mouse models have provided a wealth of information about intestinal stem cells, while less is known about human intestinal stem cells due to difficulty detecting and isolating these cells. We established an organoid repository from patient-derived adenomas,...

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Literature Corpus work: 5997a816-bc9c-547a-81c7-08ac2942f9a3
DOI: 10.1101/118034

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