Article
Intestinal stem cells and the colorectal cancer microenvironment.
World journal of gastroenterology - 28 Feb 2014
Ong Bryan A, Vega Kenneth J, Houchen Courtney W
Abstract excerpt
Colorectal cancer (CRC) remains a highly fatal condition in part due to its resilience to treatment and its propensity to spread beyond the site of primary occurrence. One possible avenue for cancer to escape eradication is via stem-like cancer cells that, through phenotypic heterogeneity, are more resilient than other tumor constituents and are key contributors to cancer growth and metastasis. These...
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