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Article

Intestinal stem cells and the colorectal cancer microenvironment.

World journal of gastroenterology - 28 Feb 2014

Ong Bryan A, Vega Kenneth J, Houchen Courtney W

Abstract excerpt

Colorectal cancer (CRC) remains a highly fatal condition in part due to its resilience to treatment and its propensity to spread beyond the site of primary occurrence. One possible avenue for cancer to escape eradication is via stem-like cancer cells that, through phenotypic heterogeneity, are more resilient than other tumor constituents and are key contributors to cancer growth and metastasis. These...

Topics

Cell Differentiation
Cell Proliferation
Colorectal Neoplasms
Epithelial-Mesenchymal Transition
Humans
Intestines
Myofibroblasts
Neoplasm Metastasis
Neoplastic Stem Cells
Paneth Cells
Phenotype

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Signal Transduction

Stem Cell Niche

Surface Properties

Tumor Microenvironment

Source

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Identifiers

PMID: 24587669
DOI: 10.3748/wjg.v20.i8.1898
PMCID: PMC3934460

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 31 Aug 2026.

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