Article

Conserved DNA-binding motif loci reflect functional transcription factor binding sites

2019-10-09

Abstract excerpt

<title>Abstract</title> <p>Background Transcription factors (TF) regulate gene expression by binding to specific DNA elements called DNA-binding motifs, or motifs. The motifs at a certain genomic locus can offer clues for predicting TFs that control target genes. However, since motifs are short nucleotide sequences and many TFs share similar motifs, they are distributed across the whole genome, making it difficul...

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Literature Corpus work: 5a317a25-baf4-58ae-b3bd-6b3507a8485a
DOI: 10.21203/rs.2.15866/v1

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