Article

Transgenic mice overexpressing Pitx2 in the atria develop tachycardia-bradycardia syndrome

2023-12-13

Abstract excerpt

Sinoatrial node (SAN) dysfunction often accompanies supraventricular tachyarrhythmias such as atrial fibrillation (AF), which is referred to as tachycardia-bradycardia syndrome (TBS). Although there have been many studies on electrical remodeling in TBS, the regulatory mechanisms that cause electrical remodeling in the SAN and atrial muscles by chronic bradycardia or tachycardia have not yet been fully investigate...

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Literature Corpus work: 33abf664-62d8-5624-97e1-0d1f3bc9f22b
DOI: 10.1101/2023.12.12.571383

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