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Article

Multiple Roles of Pitx2 in Cardiac Development and Disease

9 Oct 2017

Abstract excerpt

Cardiac development is a complex morphogenetic process initiated as bilateral cardiogenic mesoderm is specified at both sides of the gastrulating embryo. Soon thereafter, these cardiogenic cells fuse at the embryonic midline configuring a symmetrical linear cardiac tube. Left/right bilateral asymmetry is first detected in the forming heart as the cardiac tube bends to the right, and subsequently, atrial and...

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Identifiers

PMID: 29367545
DOI: 10.3390/jcdd4040016

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Related research

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