Article
Cis-effects on gene expression in the human prenatal brain associated with genetic risk for neuropsychiatric disorders.
Molecular psychiatry - 1 Jun 2021
Hall Lynsey S, Pain Oliver, O'Brien Heath E, Anney Richard, Walters James T R, Owen Michael J, O'Donovan Michael C, Bray Nicholas J
Abstract excerpt
The majority of common risk alleles identified for neuropsychiatric disorders reside in noncoding regions of the genome and are therefore likely to impact gene regulation. However, the genes that are primarily affected and the nature and developmental timing of these effects remain unclear. Given the hypothesized role for early neurodevelopmental processes in these conditions, we here define genetic predictors of...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
