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Level of Physical Activity and ApoE Status - Effects on Alzheimer’s Disease and on Mortality

2026-06-22

Abstract excerpt

<h4>Background</h4> Alzheimer’s disease and related dementias (ADRD) affect over 7.2 million Americans aged 65 and older, with the APOE ε4 allele representing the strongest known genetic risk factor. Physical activity (PA) has been associated with reduced dementia risk, but its interaction with APOE genotype remains poorly characterized in large, genomically informed cohorts. <h4>Methods</h4> We conducted a r...

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Literature Corpus work
332a71be-29d2-5835-bc42-a7571102d1c7
DOI
10.64898/2026.06.18.26355781
Open publication

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Level of Physical Activity and ApoE Status - Effects on Alzheimer’s Disease and on MortalityDOI 10.64898/2026.06.18.26355781
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