Article
Combined effects of physical activity, cognitive activity, and dietary patterns on cognitive impairment in older adults with consideration of APOE genotype: a cohort study.
Alzheimer's research & therapy - 14 Jul 2025
Zhong Wen-Fang, Wang Xiao-Meng, Chen Huan, Song Wei-Qi, Gao Jian, Chen Pei-Liang, Shen Qiao-Qiao, You Fang-Fei, Li Chuan, Lv Yue-Bin, Li Zhi-Hao, Shi Xiao-Ming, Mao Chen
Abstract excerpt
BACKGROUND: This study aims to evaluate the combination effects of physical activity (PA), cognitive activity (CA), and dietary patterns impacts cognitive impairment among older adults, and whether these associations differ by apolipoprotein E (APOE) genotype. METHODS: A total of 18,909 adults aged 65 years or older at baseline were enrolled from 1998 to 2014 years. PA and CA was assessed using scores that...
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