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Article

The effect of physical activity on cognition relative to APOE genotype (PAAD-2): study protocol for a phase II randomized control trial.

BMC neurology - 6 Jun 2020

Park Kyoung Shin, Ganesh Alexis B, Berry Nathaniel T, Mobley Yashonda P, Karper William B, Labban Jeffrey D, Wahlheim Christopher N, Williams Tomika M, Wideman Laurie, Etnier Jennifer L

Abstract excerpt

BACKGROUND: By 2050, the prevalence of Alzheimer's disease (AD) in the United States is predicted to reach 13.8 million. Despite worldwide research efforts, a cure for AD has not been identified. Thus, it is critical to identify preventive strategies that can reduce the risk of or delay the onset of AD. Physical activity (PA) has potential in this regard. This randomized clinical trial aims to (a) test the causal...

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Identifiers

PMID: 32503473
DOI: 10.1186/s12883-020-01732-1
PMCID: PMC7274941

Genes

APOE
FH

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 3 Sept 2026.

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