Article

Myeloid 12/15-LOX regulates B cell numbers and innate immune antibody levels in vivo

2017-01-04

Abstract excerpt

<h4>Background: </h4> The myeloid enzyme 12/15-lipoxygenase (LOX), which generates bioactive oxidized lipids, has been implicated in numerous inflammatory diseases, with several studies demonstrating an improvement in pathology in mice lacking the enzyme. However, the ability of 12/15-LOX to directly regulate B cell function has not been studied. <h4>Methods: </h4>: The influence of 12/15-LOX on B cell phenotyp...

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Literature Corpus work: 330d9015-adf0-56a8-8fd8-bcc0c2fc8327
DOI: 10.12688/wellcomeopenres.10308.1

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