Article

Phenotype-specific enrichment of Mendelian disorder genes near GWAS regions across 62 complex traits

2018-05-17

Abstract excerpt

<h4>ABSTRACT</h4> Although recent studies provide evidence for a common genetic basis between complex traits and Mendelian disorders, a thorough quantification of their overlap in a phenotype-specific manner remains elusive. Here, we quantify the overlap of genes identified through large-scale genome-wide association studies (GWAS) for 62 complex traits and diseases with genes known to cause 20 broad categories o...

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Literature Corpus work: 32acdb9c-52b4-5e11-9cc6-aa528873bb95
DOI: 10.1101/324558

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