Article

Prediction of Polygenic Risk Score by Machine Learning and Deep Learning Methods in Genome-wide Association Studies

2023-01-03

Abstract excerpt

Polygenic risk score (PRS) is a method that using multiple SNPs simultaneously and can be calculated as a typical disease risk score. It is useful method for precision and personalised medicine. Calculating PRS with the classical method, it is frequently used to use two different data sets which are training and testing sets. It is a disadvantage for the classical method. By using a single data set, machine learni...

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Literature Corpus work: 81789964-9771-501a-a00c-26c22aa4fde1
DOI: 10.1101/2022.12.30.522280

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