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Article

Locally constrained immune-interaction fronts at tumor–immune interfaces are associated with immunotherapy response in hepatocellular carcinoma

2026-06-15

Abstract excerpt

<title>Abstract</title> <p> <bold>Background.</bold> Spatial transcriptomics can reveal that the structural character of tumour–immune interactions—not merely cell-type abundance—may determine immunotherapy response. Existing spatial methods quantify co-localisation rather than the interaction field geometry, leaving locally constrained immune fronts analytically invisible. <bold>Methods.</bold> We developed...

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Literature Corpus work
328cfd0a-07b9-5f14-82c2-aaf314572a55
DOI
10.21203/rs.3.rs-10010055/v1
Open publication

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Locally constrained immune-interaction fronts at tumor–immune interfaces are associated with immunotherapy response in hepatocellular carcinomaDOI 10.21203/rs.3.rs-10010055/v1
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