Article

LocusPackRat: a Semi-Automated Framework for Prioritizing Candidate Genes from Large GWAS Intervals

2025-12-08

Abstract excerpt

Genome-wide association studies (GWAS) routinely implicate broad loci that span tens of megabases and contain dozens of genes, making the leap from locus to causal gene challenging, especially in model organism cohorts with reduced mapping resolution. We developed LocusPackRat, a semi-automated, easily extendible package that assembles standardized ‘packets’ of evidence to accelerate candidate gene prioritization....

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Literature Corpus work: 32695819-575b-5f2c-a1d6-05a056bfc431
DOI: 10.64898/2025.12.03.692167

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