Article

Gene prioritization in GWAS loci using multimodal evidence

2023-12-28

Abstract excerpt

<h4>ABSTRACT</h4> Genome-wide association studies (GWAS) yield large numbers of genetic loci associated with traits and diseases. Predicting the effector genes that mediate these locus associations remains challenging. Here we present the FLAMES framework, which predicts the most likely effector gene in a locus. FLAMES integrates machine learning predictions from biological data linking single nucleotide polymorph...

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Literature Corpus work: 7e0c9356-3be9-5e66-b839-5355c01d690c
DOI: 10.1101/2023.12.23.23300360

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