Article

ProGeM: A framework for the prioritisation of candidate causal genes at molecular quantitative trait loci

2017-12-08

Abstract excerpt

<h4>ABSTRACT</h4> Quantitative trait locus (QTL) mapping of molecular phenotypes such as metabolites, lipids, and proteins through genome-wide association studies (GWAS) represents a powerful means of highlighting molecular mechanisms relevant to human diseases. However, a major challenge of this approach is to identify the causal gene(s) at the observed QTLs. Here we present a framework for the “ Pr ioritisatio...

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Literature Corpus work: 5088612a-4c21-5464-999c-26ae270bc374
DOI: 10.1101/230094

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