Article
Open Targets Genetics: systematic identification of trait-associated genes using large-scale genetics and functional genomics.
Nucleic acids research - 8 Jan 2021
Ghoussaini Maya, Mountjoy Edward, Carmona Miguel, Peat Gareth, Schmidt Ellen M, Hercules Andrew, Fumis Luca, Miranda Alfredo, Carvalho-Silva Denise, Buniello Annalisa, Burdett Tony, Hayhurst James, Baker Jarrod, Ferrer Javier, Gonzalez-Uriarte Asier, Jupp Simon, Karim Mohd Anisul, Koscielny Gautier, Machlitt-Northen Sandra, Malangone Cinzia, Pendlington Zoe May, Roncaglia Paola, Suveges Daniel, Wright Daniel, Vrousgou Olga, Papa Eliseo, Parkinson Helen, MacArthur Jacqueline A L, Todd John A, Barrett Jeffrey C, Schwartzentruber Jeremy, Hulcoop David G, Ochoa David, McDonagh Ellen M, Dunham Ian
Abstract excerpt
Open Targets Genetics (https://genetics.opentargets.org) is an open-access integrative resource that aggregates human GWAS and functional genomics data including gene expression, protein abundance, chromatin interaction and conformation data from a wide range of cell types and tissues to make robust connections between GWAS-associated loci, variants and likely causal genes. This enables systematic identification...
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