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LocusPackRat: an R package to support prioritizing candidate genes from large GWAS intervals with standardized evidence aggregation.

G3 (Bethesda, Md.) - 3 Jun 2026

Gural Brian, Kimball Todd, Luu Anh N, Rau Christoph D

Abstract excerpt

Genome-wide association studies (GWAS) routinely implicate broad loci that span tens of megabases and contain dozens of genes, making the leap from locus to causal gene challenging, especially in model organism cohorts with reduced mapping resolution. We developed LocusPackRat, an easily extendable R package that assembles standardized "packets" of evidence to accelerate candidate gene prioritization. Each packet...

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Identifiers

PMID: 41902696
DOI: 10.1093/g3journal/jkag081
PMCID: PMC13232493

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 11 Sept 2026.

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