Article

Current challenges in GWAS integration and fine-mapping for variant interpretation

2026-07-08

Abstract excerpt

Over the past two decades, genome-wide association studies (GWAS) have identified thousands of trait- and disease-associated loci. However, the mechanistic understanding of these loci remains incomplete, which limits our ability to understand gene regulation and cellular programs underlying complex traits, predict disease risk, and develop therapeutics targeted to root causes. Here, we describe the current challen...

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Literature Corpus work: 22914a03-84b4-5a27-9016-f743a7d1022d
DOI: 10.64898/2026.07.04.736511

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