Article

Protein G-quadruplex interactions and their effects on phase transitions and protein aggregation

2023-09-21

Abstract excerpt

<h4>ABSTRACT</h4> The SERF family of proteins were originally discovered for their ability to accelerate amyloid formation. Znf706 is an uncharacterized protein whose N-terminus is homologous to SERF proteins. We show here that human Znf706 can promote protein aggregation and amyloid formation. Unexpectedly, Znf706 specifically interacts with stable, non-canonical nucleic acid structures known as G-quadruplexes....

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Identifiers and source

Literature Corpus work: 32347feb-199b-507f-aa83-ee76c2127667
DOI: 10.1101/2023.09.21.558871

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