Article
Capturing sex-specific and hypofertility-linked effects of assisted reproductive technologies on the cord blood DNA methylome
11 May 2023
Abstract excerpt
BACKGROUND: Children conceived through assisted reproduction are at an increased risk for growth and genomic imprinting disorders, often linked to DNA methylation defects. It has been suggested that assisted reproductive technology (ART) and underlying parental infertility can induce epigenetic instability, specifically interfering with DNA methylation reprogramming events during germ cell and preimplantation...
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