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High frequency of bedaquiline resistance in programmatically treated drug-resistant TB patients with sustained culture-positivity in Cape Town, South Africa

2022-11-14

Abstract excerpt

<h4>Introduction</h4> Bedaquiline (BDQ) is a lifesaving new tuberculosis (TB) drug undergoing global scale-up. Data on resistance emergence in programmatic settings, especially in patients resistant to other drugs with potentially weak background regimens, is scarce. Such individuals are a priority for novel drug access yet a potential source of population-level resistance. <h4>Methods</h4> We collected culture is...

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Literature Corpus work
31f1ed1a-2136-56b4-a2d2-0760d74dbd11
DOI
10.1101/2022.11.14.22282167
Open publication

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High frequency of bedaquiline resistance in programmatically treated drug-resistant TB patients with sustained culture-positivity in Cape Town, South AfricaDOI 10.1101/2022.11.14.22282167
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