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Article

Bedaquiline resistance in patients with Xpert MTB/RIF Ultra-tested rifampicin-resistant tuberculosis in the Western Cape, South Africa: a prospective study.

The Lancet. Microbe - 1 Mar 2026

Steyn Janré, Williams Jennifer, Naufal Fahd, Limberis Jason, Grobbelaar Melanie, Ismail Nabila, Ghebrekristos Yonas, Opperman Christoffel J, Nalyvayko Alina, Singh Sarishna, Colman Rebecca E, Rodwell Timothy C, Theron Grant, Warren Robin M, Metcalfe John Z

Abstract excerpt

BACKGROUND: Bedaquiline-containing regimens have been widely used to treat patients with drug-resistant tuberculosis in South Africa since 2019. We aimed to estimate the prevalence of bedaquiline resistance among patients in the Western Cape with rifampicin-resistant tuberculosis tested by Xpert MTB/RIF Ultra (Xpert). METHODS: This prospective study analysed consecutive Mycobacterium tuberculosis diagnostic...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 41724179
DOI: 10.1016/j.lanmic.2025.101293
PMCID: PMC13100955

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

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