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Recent Developments for Context Specificity in PRS

2026-04-08

Abstract excerpt

<title>Abstract</title> <p>Polygenic Risk Scores (PRS) are increasingly used in precision medicine, yet their predictive performance varies across ancestry, sex, and other contexts, raising concerns about fairness and clinical utility. Recent methodological advances aim to improve portability and fairness through ancestry-aware modelling, privacy-preserving frameworks, and more interpretable designs, on top of in...

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Literature Corpus work
31ec2eba-89e6-5e94-86a3-98e5c903114d
DOI
10.21203/rs.3.rs-9341544/v1
Open publication

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Recent Developments for Context Specificity in PRSDOI 10.21203/rs.3.rs-9341544/v1
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