Article

Dynamics of Pulsatile Activities of Arcuate Kisspeptin Neurons in Aging Female Mice

2022-08-10

Abstract excerpt

Reproductive senescence is broadly observed across mammalian females, including humans, eventually leading to a loss of fertility. The pulsatile secretion of gonadotropin-releasing hormone (GnRH), which is essential for gonad function, is primarily controlled by kisspeptin neurons in the hypothalamic arcuate nucleus (ARC kiss ), the pulse generator of GnRH. The pulsatility of GnRH release, as assessed by the amou...

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Literature Corpus work: 31813574-905d-5383-bdb9-b04d41adf934
DOI: 10.1101/2022.08.08.503241

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