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Article

Murine Arcuate Nucleus Kisspeptin Neurons Communicate with GnRH Neurons<i>In Utero</i>

5 Mar 2014

Abstract excerpt

Puberty is a transition period of reproductive development from juvenile stages to adulthood and depends upon the activity of gonadotropin-releasing hormone (GnRH) neurons. GnRH neurons are initially activated in utero but remain quiescent throughout the juvenile period. Premature reactivation of GnRH neurons results in precocious puberty in mice and humans, but the mechanisms underlying developmental control of...

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PMID: 24599473
DOI: 10.1523/jneurosci.5123-13.2014

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