Article
Estrogen Regulation of the Molecular Phenotype and Active Translatome of AVPV Kisspeptin Neurons.
Endocrinology - 1 Sept 2021
Stephens Shannon B Z, Kauffman Alexander S
Abstract excerpt
In females, ovarian estradiol (E2) exerts both negative and positive feedback regulation on the neural circuits governing reproductive hormone secretion, but the cellular and molecular mechanisms underlying this remain poorly understood. In rodents, estrogen receptor α-expressing kisspeptin neurons in the hypothalamic anteroventral periventricular region (AVPV) are prime candidates to mediate E2 positive feedback...
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