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Association of human leukocyte antigen polymorphisms with occult hepatitis B virus infection in a Shaanxi Han population.

The journal of gene medicine - 1 Sept 2017

Wang Tianju, Shen Chunmei, Chen Liping, Liu Sheng, Ji Yanhong

Abstract excerpt

BACKGROUND: Occult hepatitis B virus (HBV) infection (OBI) is defined as HBV DNA detection in serum or in the liver by sensitive diagnostic tests in HBV surface antigen (HBsAg) negative patients with or without serologic markers of previous HBV exposure. Because the human leukocyte antigen (HLA) system is an integral component of the immune response, we hypothesized that the highly polymorphic HLA genes were the...

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Case-Control Studies
China
DNA, Viral
Hepatitis B
Hepatitis B virus

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PMID: 28940887
DOI: 10.1002/jgm.2987

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