Article

DEPTH2 score was associated with cell proliferation and immune cell infiltrations but not with systemic treatment response in breast cancer

2024-11-20

Abstract excerpt

<title>Abstract</title> <p>Intratumoral genomic heterogeneity (ITGH), the existence of genotypic and phenotypic variation within an individual tumor, is known to be a key mechanism in treatment resistance. Deviating gene Expression Profiling Tumor Heterogeneity 2 (DEPTH2) algorithm was developed to estimate ITGH using solely RNA expression data unlike the others that require both DNA- and RNA-expression data. Tot...

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Literature Corpus work: 3164e617-ddcb-557f-8773-1e8ea5839e30
DOI: 10.21203/rs.3.rs-5260856/v1

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