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Article

Functional Genomic Complexity Defines Intratumor Heterogeneity and Tumor Aggressiveness in Liver Cancer

2019-04-20

Abstract excerpt

<h4>ABSTRACT</h4> <h4>Background</h4> Chronic inflammation and chromosome aneuploidy are major traits of primary liver cancer (PLC), which represent the second most common cause of cancer related death worldwide. Increased cancer fitness and aggressiveness of PLC may be achieved by enhancing tumoral genomic complexity that alters tumor biology. <h4>Method</h4> Here, we developed a scoring method, namely functio...

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Literature Corpus work
23aa0a03-521e-5a0b-906a-dbc0958a17aa
DOI
10.1101/614057
Open publication

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Functional Genomic Complexity Defines Intratumor Heterogeneity and Tumor Aggressiveness in Liver CancerDOI 10.1101/614057
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